Eurofins DiscoverX CSK Protein, Active

Product Code. 17360194

Brand: Eurofins DiscoverX 14458

Description

Active, recombinant full-length human CSK, containing an N-terminal GST-tag incorporating a PreScission Protease cleavage site, for use in Kinase Assays.

CSK (C-SRC, c-src tyrosine kinase) is a non-receptor tyrosine kinase that catalyzes the tyrosine phosphorylation of Src family members at C-terminal, promoting an intramolecular association between the phosphotyrosine and the Src homology 2 (SH2) domain and negatively regulating Src catalytic activity in vivo. Although CSK has substantial homology to Src kinases, it lacks the C-terminal regulatory tyrosine found in Src kinases.

GenBank X60114 (CDS GB 30314)

Specifications

• Formulation: mg/mL of enzyme in 50 mM Tris/HCl, pH 7.5, 0.1 mM EGTA, 150 mM NaCl, 1 mM benzamidine, 0.03% Brij-35, 0.2 mM PMSF, 0.1% 2-mercaptoethanol, 50% glycerol. Liquid at -20°C
• Molecular Weight (g/mol): 77.6 kDa
• Quantity: 10 μg
• Species: Human
• Recombinant: Recombinant
• Protein Tag: N-terminal GST incorporating PreScission Protease cleavage site
• Expression System: Recombinant enzyme expressed in E. coli cells
• Protein Form: Full-length
• Purity or Quality Grade: ≥75%
• Protein: CSK, active