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Invitrogen™ CRMP3 Recombinant Rabbit Monoclonal Antibody (23GB1510), Invitrogen™

Description
Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-3 is expressed transiently in developing spinal cord and selectively in the postnatal cerebellum.
Specifications
Specifications
| Antigen | CRMP3 |
| Applications | Flow Cytometry, Western Blot, Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Clone | 23GB1510 |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | DPYSL4 |
| Gene Accession No. | O14531, O35098, Q62951 |
| Gene Alias | AI173505; Collapsin response mediator protein 3; CRMP3; CRMP-3; dihydropyrimidinase like 4; dihydropyrimidinase-like 4; dihydropyrimidinase-related protein 4; DPY4; Dpys4; DPYSL4; DRP-4; ULIP4; ULIP-4; ULIP4 protein; unc-33-like phosphoprotein 4; UNC33-like phosphoprotein 4 |
| Gene Symbols | DPYSL4 |
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