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Invitrogen™ Cripto Monoclonal Antibody (3A6)
Description
MA5-15843 targets TDGF1 in WB applications and shows reactivity with Human samples. The MA5-15843 immunogen is purified recombinant fragment of human TDGF1 expressed in E. Coli. .
Cripto (TDGF1) is a GPI-anchored cell membrane proetin involved in Nodal signaling. Cell associated TDGF1 acts as a a Nodeal coreceptor in cis. Shedding of TDGF1 by TMEM8A modulated Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells. TDGF1 is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers.
Specifications
Specifications
| Antigen | Cripto |
| Applications | Western Blot |
| Classification | Monoclonal |
| Clone | 3A6 |
| Concentration | Conc. Not Determined |
| Conjugate | Unconjugated |
| Formulation | ascites with 0.03% sodium azide |
| Gene | TDGF1 |
| Gene Accession No. | P13385 |
| Gene Alias | CR; CR1; CRGF; CRIPTO; cripto growth factor; Cripto-1; cripto-1 growth factor; Cripto-3; epidermal growth factor-like Cripto protein; epidermal growth factor-like cripto protein CR1; Tdgf1; TDGF2; teratocarcinoma-derived growth factor; teratocarcinoma-derived growth factor 1; TERATOCARCINOMA-DERIVED GROWTH FACTOR PRECURSOR (EPIDERMAL GROWTH FACTOR-LIKE CRIPTO PROTEIN) (CRIPTO GROWTH FACTOR) |
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