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  6. Invitrogen™ CRACC Recombinant Mouse Monoclonal Antibody (K8U029_14H8)

Invitrogen™ CRACC Recombinant Mouse Monoclonal Antibody (K8U029_14H8)
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Product Code. 30827777
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30826621 50 μL
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Product Code. 30827777 Supplier Invitrogen™ Supplier No. MA564460

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Description

Mouse Recombinant Monoclonal Antibody

Immunogen sequence: EKKRVDICRE TPNICPHSGE NTEYDTIPHT NRTILKEDPA NTVYSTVEIP KKMENPHSLL TMPDTPRLFA Highest antigen sequence identity to the following orthologs: Mouse - 52%, Pig - 53%, Cynomolgus monkey - 87%.

SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain. Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro). SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level than isoform 1. There are three named isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CRACC
Applications Immunohistochemistry (Paraffin)
Classification Recombinant Monoclonal
Clone K8U029_14H8
Concentration 0.31 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.5% BSA, 50% glycerol and 0.09% sodium azide
Gene SLAMF7
Gene Accession No. Q9NQ25
Gene Alias 19A; 19A24; 19A24 protein; 4930560D03Rik; CD2 subset 1; CD2-like receptor activating cytotoxic cells; CD2-like receptor-activating cytotoxic cells; CD319; CRACC; CS1; Leukocyte cell-surface antigen; membrane protein FOAP-12; Novel Ly9; novel LY9 (lymphocyte antigen 9) like protein; protein 19A; RGD1560190; SLAM family member 7; SLAMF7; UNQ576/PRO1138
Gene Symbols SLAMF7
Host Species Mouse
Immunogen Recombinant human SLAMF7 (aa 261-330).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57823
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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