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CP-724714, MedChemExpress

Product Code. p-200097534
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Product Code. 16486128

Brand: Medchem Express HY14674

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Description

MedChemExpress CP-724714 is a potent, selective and orally active ErbB2 (HER2) tyrosine kinase inhibitor, with an IC50 of 10 nM. CP-724714 displays a marked selectivity against EGFR kinase (IC50=6400 nM). CP-724714 potently inhibits ErbB2 receptor autophosphorylation in intact cells. Antitumor activities.

CP-724714 is a potent, selective and orally active ErbB2 (HER2) tyrosine kinase inhibitor, with an IC50 of 10 nM. CP-724714 displays a marked selectivity against EGFR kinase (IC50=6400 nM). CP-724714 potently inhibits ErbB2 receptor autophosphorylation in intact cells. Antitumor activities.

Specifications

Chemical Name or Material CP-724714
CAS 383432-38-0
Color Yellow
Purity Grade Notes Research
Molecular Formula C27H27N5O3
Quantity 10 mg
Solubility Information DMSO : ≥ 50 mg/mL (106.49 mM)
SMILES O=C(COC)NC/C=C/C1=CC2=C(N=CN=C2C=C1)NC3=CC=C(C(C)=C3)OC4=CC=C(N=C4)C.[(E)]
Molecular Weight (g/mol) 469.53
Formula Weight 469.53
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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