Invitrogen™ COX8A Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA575651

Product Code. 15972175

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. The COX8 (cytochrome c oxidase subunit VIII) subunits are nuclear and have muscle and non-muscle-specific isoforms. COX8 exists as three isoforms: COX8a, a liver and heart isoform, Cox8b, a heart-specific isoform, and Cox8c, whose expression pattern has yet to be elucidated. All three Cox8 isoforms exists as components of the COX complex and play an important role in electron transport.

Specifications

• Antigen: COX8A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: COX8A
• Gene Alias: COX; COX VIII-L; COX8; COX8-2; COX8A; Cox8l; cytochrome c oxidase polypeptide VIII-liver; Cytochrome c oxidase polypeptide VIII-liver/heart; cytochrome c oxidase subunit 8-2; cytochrome c oxidase subunit 8A; cytochrome c oxidase subunit 8A (ubiquitous); cytochrome c oxidase subunit 8A, mitochondrial; cytochrome c oxidase subunit VIII; cytochrome c oxidase subunit VIIIa; cytochrome c oxidase subunit VIIIA (ubiquitous); VIII; VIII-L
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12868, 1351, 171335
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P10176, P80433, Q64445
• Gene Symbols: COX8A
• Immunogen: Synthetic peptide corresponding to residues in Human COX8A.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG