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Invitrogen™ COX6C Recombinant Rabbit Monoclonal Antibody (K01_1Q11)
Description
Immunogen sequence: DFEEMRKAGI FQSVK.
Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12.
Specifications
Specifications
| Antigen | COX6C |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | K01_1Q11 |
| Concentration | 0.3 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 50mM tris glycine with 150mM NaCl, 0.05% BSA, 40% glycerol and 0.01% sodium azide; pH 7.4 |
| Gene | COX6C |
| Gene Accession No. | P09669, P11951, Q9CPQ1 |
| Gene Alias | COVIc; Cox6c; Cox6c2; COX-VIc; cytochrome c oxidase polypeptide VIc; Cytochrome c oxidase polypeptide VIc-2; cytochrome c oxidase subunit 6C; Cytochrome c oxidase subunit 6C-2; cytochrome c oxidase subunit VIc; cytochrome c oxidase subunit VIc preprotein; cytochrome c oxidase, subunit VIc; cytochrome oxidase subunit VIc; EC 1.9.3.1 |
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