Copanlisib, MedChemExpress

Product Code. 16472567

Brand: Medchem Express HY15346

Description

MedChemExpress Copanlisib (BAY 80-6946) is a potent, selective and ATP-competitive pan-class I PI3K inhibitor, with IC50s of 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ, respectively. Copanlisib has more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR. Copanlisib has superior antitumor activity.

Copanlisib (BAY 80-6946) is a potent, selective and ATP-competitive pan-class I PI3K inhibitor, with IC50s of 0.5 nM, 0.7 nM, 3.7 nM and 6.4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ, respectively. Copanlisib has more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR. Copanlisib has superior antitumor activity.

Specifications

• Chemical Name or Material: Copanlisib
• CAS: 1032568-63-0
• Color: Light Yellow
• Purity Grade Notes: Research
• Molecular Formula: C₂₃H₂₈N₈O₄
• Quantity: 50 mg
• Synonym: BAY 80-6946
• Solubility Information: 1M HCl : 100 mg/mL (208.11 mM; Need ultrasonic) ∣DMSO : 1 mg/mL (2.08 mM; Need ultrasonic) ∣H2O : 0.67 mg/mL (1.39 mM; Need ultrasonic)
• SMILES: O=C(C1=CN=C(N)N=C1)NC2=NC3=C(OC)C(OCCCN4CCOCC4)=CC=C3C5=NCCN25
• Molecular Weight (g/mol): 480.52
• Formula Weight: 480.52
• Percent Purity: 98.02%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Cancer-Kinase/protease

Research purposes only