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Invitrogen™ Contactin 2 Polyclonal Antibody
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Product Code. 15719530 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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15719530 100 μL 100µL
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Product Code. 15719530 Supplier Invitrogen™ Supplier No. PA551571

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PASPSANATT MKPPPRRPPG NISWTFSSSS LSIKWDPVVP FRNESAVTGY KMLYQNDLHL TPTLHLTGKN WIEIPVPEDI GHALVQIRTT GPGGDGIPAE VHIVRNGGTS MMVENMAVRP APHPGTVISH SVAMLIL Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 84%.

Contactin 2 (CNTN2, transiently-expressed axonal glycoprotein, AXT, TAX, TAX1, TAG-1, axonin 1) is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunoglobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding). The Contactin 2 heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains. The Contactin 2 homophilic (Contactin 2/Contactin 2) binding site is localized to the FNIII domain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Contactin 2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CNTN2
Gene Accession No. Q02246
Gene Alias Axonal glycoprotein TAG-1; axonin; Axonin 1; Axonin1; axonin-1; axonin-1 cell adhesion molecule; AXT; Cntn2; contactin 2; contactin 2 (axonal); contactin 2 (transiently expressed); Contactin2; contactin-2; D130012K04Rik; DKFZp781D102; FAME5; MGC157722; TAG1; TAG-1; TAG-564; Tax; TAX1; TAX-1; transient axonal glycoprotein 1; transiently-expressed axonal glycoprotein
Gene Symbols CNTN2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human Contactin 2. Recombinant protein control fragment (Product #RP-94791).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6900
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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