Invitrogen™ COMMD5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA583847

Product Code. 16310805

Description

Immunogen sequence: TFRDQLQELC IPQDLVGDLA SVVFGSQRPL LDSVAQQQGA WLPHVADF Highest antigen sequence indentity to the following orthologs: Mouse - 73%, Rat - 73%.

COMMD5 is a protein coding gene. May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis. Down-regulates activation of NF-kappa-B.

Specifications

• Antigen: COMMD5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: COMMD5
• Gene Alias: 2310065H03Rik; AI854466; COMM domain containing 5; COMM domain-containing protein 5; COMMD5; D15Ertd81e; FLJ13008; HCARG; HT002; hypertension-related calcium regulated; hypertension-related calcium-regulated gene protein; hypertension-related, calcium regulated
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 28991
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9GZQ3
• Gene Symbols: COMMD5
• Immunogen: Recombinant protein corresponding to Human COMMD5. Recombinant protein control fragment (Product #RP-99259).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG