Colistin sulfate, Thermo Scientific™

Colistin Sulfate salt (2:5), CAS # 1264-72-8, (synonym: Polymyxin E Complex), is a complex mixture of antibiotics, with Colistin A and B being the primary components. It has anti-bacterial activity against Gram-positive and Gram-negative bacteria and may also be used as a neuromuscular blocker.

Brand:  Thermo Scientific Alfa Aesar J60915.03

Product Code. 15463599

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General description

• Colistin Sulfate salt is a stable, cationic, water-soluble, white powder composed of over 30 components

• Originally isolated from B. polymyxa, it inhibits the growth of the Gram-negative (e.g. E. coli, P. aeruginosa, P. fluorescens, and S. enterica), and Gram-positive bacteria (e.g. L. lactis, P. polymyxa, P. acidilactici, and S. aureus) by permeabilizing the bacterial cell membrane

Applications

• Colistin Sulfate has potent anti-endotoxin activity rendered through its ability to bind lippopolysaccharides that make up bacterial endotoxins

• This compound is often used in the management of multi-drug resistant Gram-negative infections

Specifications

• CAS: 1264-72-8
• Quantity: 1g
• UN Number: UN2811
• Synonym: Polymyxin E
• Chemical Name or Material: Colistin sulfate

• Color: White
• MDL Number: MFCD00146495
• Merck Index: 14,2479
• Solubility Information: Soluble in water

Safety and Handling

Product Identifier

• Colistin sulphate

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3

Hazard Statement

• H301-Toxic if swallowed.

Precautionary Statement

• P264-Wash face, hands and anyexposed skin thoroughly after handling.
• P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /

Supplemental information

• MIXTURE LIST-Contains : Colistin, sulphate