Invitrogen™ COL4A6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA599609

Product Code. 16673855

Description

Antibody detects endogenous levels of total COL4A6.

Type I collagen, the fibrillar collagen found in most connective tissues, and the only component of the collagen found in cartilage. Mutations in this gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Specifications

• Antigen: COL4A6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: COL4A6
• Gene Alias: BB116301; Col4a6; Collagen 4; Collagen alpha-6(IV) chain; collagen IV, alpha-6 polypeptide; collagen of basement membrane, alpha-6; collagen type IV alpha 6 chain; collagen, type IV, alpha 6; CXDELq22.3; DELXq22.3; DFNX6; dJ889N15.4 (Collagen Alpha 6(IV)); procollagen type IV alpha 6; procollagen, type IV, alpha 6
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1288, 363458, 94216
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q14031
• Gene Symbols: COL4A6
• Immunogen: A synthesized peptide derived from human COL4A6(Accession Q14031), corresponding to amino acid residues L1064-D1114.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG