Invitrogen™ COL15A1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5115179

Product Code. 17247943

Description

Antibody detects endogenous levels of total Endostatin.

This gene encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones so it may function to adhere basement membranes to underlying connective tissue stroma. The proteolytically produced C-terminal fragment of type XV collagen is restin, a potentially antiangiogenic protein that is closely related to endostatin. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration.

Specifications

• Antigen: COL15A1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: COL15A1
• Gene Alias: COFA1; COL15A1; Collagen alpha-1(XV) chain; collagen type XV alpha 1 chain; collagen type XV proteoglycan; collagen XV, alpha-1 polypeptide; collagen, type XV, alpha 1; endostatin-XV; procollagen type XV; procollagen, type XV; Related to endostatin; Restin; Restin-2; Restin-3; Restin-4; Restin-I; Restin-II; Restin-III; Restin-IV; type XV collagen
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12819, 1306, 298069
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O35206, P39059
• Gene Symbols: COL15A1
• Immunogen: A synthesized peptide derived from human COL15A1(Accession P39059), corresponding to amino acid residues A272-I322.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG