CNTF Polyclonal Antibody, Invitrogen™

Sheep Polyclonal Antibody

Brand:  Invitrogen PA118365

Product Code. 11532012

Description

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20 °C for a higher stability, and at 4 °C with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles. Glycerol (1:1) may be added for an additional stability.

The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.

Specifications

• Antigen: CNTF
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CNTF
• Gene Alias: AI429687; Ciliary neurotrophic factor; ciliary neurotropic factor; Cntf; HCNTF; H-CNTF
• Host Species: Sheep
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Concentration: Conc. Not Determined
• Formulation: whole serum with no preservative
• Gene Accession No.: P20294, P26441, P51642
• Gene Symbols: CNTF
• Immunogen: Recombinant human CNTF.
• Regulatory Status: RUO
• Gene ID (Entrez): 1270, 12803, 25707
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized