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Invitrogen™ CNTF Monoclonal Antibody (34738)
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Product Code. 15533422
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Quantity:
500 μg
Unit Size:
500µg
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Product Code. Quantity unitSize
15533422 500 μg 500µg
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Product Code. 15533422 Supplier Invitrogen™ Supplier No. MA523730

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Description

Mouse Monoclonal Antibody

In sandwich ELISAs, less than 3% cross-reactivity with recombinant human CNTF is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <1.0 EU per 1 μg of the antibody by the LAL method.

The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CNTF
Applications ELISA, Neutralization
Classification Monoclonal
Clone 34738
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene CNTF
Gene Accession No. P20294
Gene Alias AI429687; Ciliary neurotrophic factor; ciliary neurotropic factor; Cntf; HCNTF; H-CNTF
Gene Symbols CNTF
Host Species Mouse
Immunogen E. coli-derived recombinant rat CNTF Ala2-Met200.
Purification Method Protein A/G
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25707
Target Species Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG2b
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