CMPK2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA559570

Product Code. 15777421

Description

Immunogen sequence: ECTSFIPEAR AVLDLVDQCP KQIQKGKFQV VAIEGLDATG KTTVTQSVAD SLKAVLLKSP PSCIGQWRKI FDDEPTIIRR AFYSLGNYIV ASEIAKESAK SPV Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 85%.

UMP-CMP kinase 2 (CMPK2) is the first nucleoside monophosphate kinase that has been identified in human mitochondria. It is a component of the salvage pathway for nucleotide synthesis that may participate in terminal differentiation of monocytic cells. There are two distinct domains of CMPK2: the N-terminal domain with unknown function and the C-terminal domain with the kinase function, suggesting that CMPK2 may be a bifunctional protein with other biological functions in addition to its UMP-CMP kinase activity. CMPK2 may participate in dUTP and dCTP synthesis and is responsible for phosphorylation of dCMP and dUMP in mitochondria. CMPK2 is actively involved in macrophage activation and the inflammatory response

Specifications

• Antigen: CMPK2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CMPK2
• Gene Alias: TMPK2, TYKi, UMP-CMPK2, UMP-CMP kinase 2, mitochondrial, cytidylate kinase 2, mitochondrial UMP-CMP kinase, thymidine monophosphate kinase 2, thymidylate kinase family LPS-inducible member
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 129607
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q5EBM0
• Gene Symbols: CMPK2
• Immunogen: Recombit protein corresponding to Human CMPK2
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Research Use Only