missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 30000762

Tocris Bioscience™ CMPI hydrochloride
GREENER_CHOICE

Product Code. 30000762
Click to view available options
Quantity:
10 mg
Unit Size:
10mg
This item is not returnable. View return policy

Product Code. 30000762

Brand: Tocris Bioscience™ 5963/10

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Potent positive allosteric modulator of α4β2 nAChRs; also inhibitor of (α4)2(β2)3, muscle-type and Torpedo nAChRs

Potent positive allosteric modulator of α4β2 nAChRs (EC50 values are 20 and 18 nM for rat and human, respectively). Selective for hα4β2 over hα3β2, hα3β4 and hα7. Inhibits (α4)2(β2)3, muscle-type and Torpedo nAChRs (IC50 values are 0.5, 0.7 and 0.2 μM, respectively), but not (α4)3(β2)2 receptors. Exhibits ability to photoincorporate into aliphatic and nucleophilic amino acid side chains.
TRUSTED_SUSTAINABILITY

Specifications

CAS 2250025-94-4
Quantity 10 mg
Solubility Soluble to 50mM in water and to 100mM in DMSO
Formula Weight 379.28
Physical Form Solid
Purity >98%
Chemical Name or Material 3-(2-Chlorophenyl)-5-(5-methyl-1-(piperidin-4-yl)-1H-pyrazol-4-yl)isoxazole hydrochloride
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.