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  8. CM-579 trihydrochloride, MedChemExpress

CM-579 trihydrochloride, MedChemExpress

Product Code. p-200099509
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Product Code. 16451137

Brand: Medchem Express HY117421A

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Description

MedChemExpress CM-579 trihydrochloride is a first-in-class reversible, dual inhibitor of G9a and DNMT, with IC50 values of 16 nM, 32 nM for G9a and DNMT, respectively. Has potent in vitro cellular activity in a wide range of cancer cells.

CM-579 trihydrochloride is a first-in-class reversible, dual inhibitor of G9a and DNMT, with IC50 values of 16 nM, 32 nM for G9a and DNMT, respectively. Has potent in vitro cellular activity in a wide range of cancer cells.

Specifications

Chemical Name or Material CM-579 trihydrochloride
Color Deep Yellow
Purity Grade Notes Research
Molecular Formula C29H43Cl3N4O3
Quantity 50 mg
Solubility Information H2O : 37.5 mg/mL (62.29 mM; Need ultrasonic) ∣DMSO : 33.33 mg/mL (55.36 mM; Need ultrasonic)
SMILES CN1CCC(CNC2=CC(C3=CC=C(C)O3)=NC4=CC(OCCCN5CCCC5)=C(OC)C=C24)CC1.Cl.Cl.Cl
Molecular Weight (g/mol) 602.04
Formula Weight 602.04
Percent Purity 98.02%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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