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  6. ClozapineClozapine N-oxide, MedChemExpress

ClozapineClozapine N-oxide, MedChemExpress

Product Code. 16493317
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Product Code. 16493317

Brand: Medchem Express HY17366

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Description

MedChemExpress Clozapine N-oxide is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide can cross the blood-brain barrier. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor (EC50=11 nM) agonist.

Clozapine N-oxide is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide can cross the blood-brain barrier. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor (EC50=11 nM) agonist.

Specifications

Chemical Name or Material ClozapineClozapine N-oxide
Physical Form Solid
CAS 34233-69-7
Color Yellow
Quantity 50 mg
Purity Grade Notes Research
Molecular Formula C18H19ClN4O
For Use With (Application) Neuroscience-Neuromodulation
Solubility Information DMSO : ≥ 100 mg/mL (291.70 mM) ∣H2O : 1 mg/mL (2.92 mM; Need ultrasonic)
SMILES [O-][N+]1(C)CCN(C2=NC3=CC(Cl)=CC=C3NC4=CC=CC=C42)CC1
Molecular Weight (g/mol) 342.82
Formula Weight 342.82
Percent Purity 99.25%
Grade Research
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Research purposes only

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