Clozapine, MedChemExpress

Product Code.	Quantity	unitSize
16456486	100 mg	100mg
16441419	1 g	1g
16401736	500 mg	500mg
16488687	5 g	5g

Product Code. 16456486

Brand: Medchem Express HY14539

Description

MedChemExpress Clozapine (HF 1854) is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors. Clozapine is a potent antagonist of dopamine D2 with a Ki of 75 nM. Clozapine inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor with Kis of 9.5 nM and 4 nM, respectively. Clozapine is also a potent and selective agonist at the muscarinic M4 receptor (EC50=11 nM).

Clozapine (HF 1854) is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors. Clozapine is a potent antagonist of dopamine D2 with a Ki of 75 nM. Clozapine inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor with Kis of 9.5 nM and 4 nM, respectively. Clozapine is also a potent and selective agonist at the muscarinic M4 receptor (EC50=11 nM).

Specifications

• Chemical Name or Material: Clozapine
• CAS: 5786-21-0
• Color: Light Yellow
• Purity Grade Notes: Research
• Molecular Formula: C₁₈H₁₉ClN₄
• Quantity: 100 mg
• Synonym: HF 1854
• Solubility Information: DMSO : 50 mg/mL (152.99 mM; Need ultrasonic)
• SMILES: CN1CCN(CC1)C2=NC3=CC(Cl)=CC=C3NC4=CC=CC=C42
• Molecular Weight (g/mol): 326.82
• Formula Weight: 326.82
• Percent Purity: 99.74%
• Grade: Research
• Physical Form: Solid
• For Use With (Application): Neuroscience-Neurodegeneration

Research purposes only