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Closantel, MedChemExpress

Product Code. 16491886
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Product Code. 16491886 Supplier Medchem Express Supplier No. HY17596

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Description

MedChemExpress Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.

Closantel

Specifications

Chemical Name or Material Closantel
Physical Form Solid
CAS 57808-65-8
Color Off-White
Quantity 500 mg
Purity Grade Notes Research
Molecular Formula C22H14Cl2I2N2O2
For Use With (Application) COVID-19-immunoregulation
Solubility Information DMSO : ≥ 49 mg/mL (73.90 mM) ∣H2O : 1 mg/mL (1.51 mM; ultrasonic and warming and heat to 80°C)
SMILES O=C(NC1=CC(Cl)=C(C(C2=CC=C(Cl)C=C2)C#N)C=C1C)C3=CC(I)=CC(I)=C3O
Molecular Weight (g/mol) 663.07
Formula Weight 663.07
Percent Purity 98.0%
Grade Research
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