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Tocris Bioscience™ Clemizole hydrochloride

TRPC5 blocker; also H1 antagonist

Specifications

Purity >99%
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Description

Description

TRPC5 channel blocker (IC50 values are 1.1, 6.4, 9.1, 11.3 and 26.5 μM for TRPC5, TRPC4, TRPC3, TRPC6 and TRPC7 respectively). Exhibits minimal effect on TRPM3, TRPM8 and TRPV1-4 channels. Also histamine H1 receptor antagonist and anticonvulsant in zebrafish Dravet syndrome model.
Specifications

Specifications

>99%
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