Invitrogen™ CLEC5A Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5114187

Product Code. 17162044

Description

Immunogen sequence: NTPEKLKFLQ DITDAEKYFI GLIYHREEKR WRWINNSVFN GNVTNQNQNF For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 93%; Dog: 86%; Horse: 86%; Human: 100%; Pig: 79%; Rat: 79%; Yeast: 83%.

Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation. Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.

Specifications

• Antigen: CLEC5A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CLEC5A
• Gene Alias: CLEC5A; Clecsf5; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5; C-type lectin domain family 5 member A; C-type lectin domain family 5, member a; C-type lectin superfamily member 5; Ly100; Mdl1; MDL-1; myeloid DAP12-associating lectin 1; myeloid DAP12-associating lectin-1; type II transmembrane protein MDL-1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23601
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9NY25
• Gene Symbols: CLEC5A
• Immunogen: Immunogen sequence: NTPEKLKFLQ DITDAEKYFI GLIYHREEKR WRWINNSVFN GNVTNQNQNF (aa 110-159).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG