CLEC4M, anti-Human, Clone: 16E7, Abnova™

Monoclonal Antibody

Brand:  Abnova RAB00096.200ug

Product Code. 16082138

Specifications

• Antigen: CLEC4M
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: In PBS, pH 7.2 (0.02% Proclin 300).
• Gene Alias: CD209L/CD299/DC-SIGN2/DC-SIGNR/DCSIGNR/HP10347/L-SIGN/LSIGN/MGC129964/MGC47866
• Immunogen: Original antibody is raised against human CD299.
• Regulatory Status: RUO
• Gene ID (Entrez): 10332
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG κ

• Applications: Flow Cytometry, Immunohistochemistry
• Clone: 16E7
• Dilution: Flow Cytometry (1 ug/mL) Immunohistochemistry (5 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: C-type lectin domain family 4, member M
• Gene Symbols: CLEC4M
• Quantity: 200 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes human CLEC4M, which is an oligomeric type II transmembrane protein with a C-type lectin extracellular domain, the expression of which is restricted to immature DC, macrophages in the lung, and endothelial cells in the liver. It binds ICAM-3 and ICAM-7 to mediate the interaction of DC with T lymphocytes and endothelial cells in the initial stages of immune response and in the migratory behavior of DC. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection.
• Content And Storage: Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
• Form: Liquid