Invitrogen™ CLCNKB Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5119867

Product Code. 17791264

Description

Positive Control: Mouse testis tissue lysate, rat testis tissue lysate, MCF-7 cell lysate, human kidney tissue, human seminoma tissue, MG-63, A549. Subcellular Location: Cell membrane.

Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III Bartter Syndrome. CLCNKA and CLCNKB are closely related (94% sequence identity), tightly linked (separated by 11 kb of genomic sequence) and are both expressed in mammalian kidney.

Specifications

• Antigen: CLCNKB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CLCNKB
• Gene Alias: chloride channel; chloride channel K1-like; putative basolateral cTAL chloride channel ClC-Ka; chloride channel K2; chloride channel Ka; Chloride channel Kb; chloride channel protein ClC-Ka; Chloride channel protein ClC-Kb; chloride channel, kidney, B; chloride channel, voltage-sensitive Ka; chloride channel, voltage-sensitive Kb; chloride voltage-gated channel Kb; clC-K1; Clck2; ClC-K2; ClC-K2L; Clc-Ka; CLCKB; ClC-Kb; CLCNK; Clcnk1l; CLCNKA; Clcnkb; hClC-Kb; LOC100730738; MGC24087; putative basolateral mTAL chloride channel ClC-Ka; RP11-5P18.8
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1188, 56365, 79430
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P51801, P51802, Q9WUB6
• Gene Symbols: CLCNKB
• Immunogen: Recombinant protein within C-terminal human CLCNKB from aa520-aa687.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG