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Cl-amidine hydrochloride, MedChemExpress

Product Code. 16453088
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Quantity:
5 mg
10 mg
Unit Size:
10mg
5mg
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Product Code. 16453088

Brand: Medchem Express HY100574A

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Description

MedChemExpress Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively.

Cl-amidine hydrochloride induces apoptosis in cancer cells. Cl-amidine hydrochloride induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine hydrochloride prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model.

Specifications

Chemical Name or Material Cl-amidine hydrochloride
Physical Form Solid
CAS 1373232-26-8
Color White
Quantity 10 mg
Purity Grade Notes Research
Molecular Formula C14H20Cl2N4O2
For Use With (Application) COVID-19-immunoregulation
Solubility Information DMSO : 100 mg/mL (287.99 mM; Need ultrasonic) ∣H2O : 50 mg/mL (143.99 mM; Need ultrasonic)
SMILES O=C(N[C@H](C(N)=O)CCCNC(CCl)=N)C1=CC=CC=C1.[H]Cl
Molecular Weight (g/mol) 347.24
Formula Weight 347.24
Percent Purity 95.0%
Grade Research
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Research purposes only

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