CKAP4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16876394	Proteintech 16686-1-AP-20UL	20 μL
16866394	Proteintech 16686-1-AP-150UL	150 μL

Description

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

Specifications

• Antigen: CKAP4
• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry, Immunofluorescence, Western Blot, Immunoprecipitation
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Mouse, Rat, Human
• Gene Accession No.: Q07065, Q8BMK4
• Gene ID (Entrez): 10970, 216197, 362859
• Immunogen: CKAP4 Fusion Protein Ag10019
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: CKAP4

• Concentration: 0.23 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: 63 kDa membrane protein, CKAP4, CLIMP 63, ERGIC 63, p63
• Gene Symbols: Ckap4
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody