Invitrogen™ CKAP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA535867

Product Code. 15547341

Description

Recommended positive controls: Raji, NCI-H929. Predicted reactivity: Mouse (82%), Rat (80%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.

Specifications

• Antigen: CKAP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CKAP2
• Gene Alias: AI461656; AW228814; Ckap2; CTCL tumor antigen se20-10; cytoskeleton associated protein 2; cytoskeleton-associated protein 2; LB1; se20-10; TMAP; Tumor- and microtubule-associated protein; tumor-associated microtubule-associated protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26586
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8WWK9
• Gene Symbols: CKAP2
• Immunogen: Recombinant protein encompassing a sequence within the center region of human CKAP2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG