Invitrogen™ CK1 gamma-1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA536284

Product Code. 15567601

Description

This antibody detects endogenous protein at a molecular weight of 49 kDa. Purity is >95% by SDS-PAGE.

Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/ threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKI alpha, gamma, epsilon and delta, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an alpha2 beta2 or an alpha alpha' beta2 structure. The alpha catalytic subunit is stimulated by the beta regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.

Specifications

• Antigen: CK1 gamma-1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Csnk1g1
• Gene Alias: 9130020E21Rik; casein kinase 1 gamma 1; casein kinase 1, gamma 1; casein kinase I isoform gamma-1; casein kinase I, gamma 1; CK I gamma1; CK1G1; CK1gamma1; CKI gamma 1; CKI gamma1; CK-I gamma1; CKI- gamma1; CKI gamma-1; CKI-gamma 1; CKI-gamma-1; CSNK1G1; KC1G1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 214897, 53944, 64086
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q62761, Q8BTH8, Q9HCP0
• Gene Symbols: Csnk1g1
• Immunogen: Synthetic peptide corresponding to the N-terminual of human Casein Kinase I gamma1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG