Invitrogen™ CIRBP Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5119039

Product Code. 17720454

Description

CIRBP Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

CIRBP is cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator and seems to play an essential role in cold-induced suppression of cell proliferation. It binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. This protein acts as a translational repressor and promotes assembly of stress granules (SGs), when overexpressed.

Specifications

• Antigen: CIRBP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CIRBP
• Gene Alias: A18 hnRNP; A18HNRNP; CIRBP; CIRP; cold inducible RNA binding protein; cold inducible RNA-binding protein; cold-inducible RNA-binding protein; glycine-rich RNA binding protein; glycine-rich RNA-binding protein CIRP; R74941; testicular tissue protein Li 39
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 100522851, 1153, 12696
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: P60824, Q14011
• Gene Symbols: CIRBP
• Immunogen: Recombinant protein Cold Inducible RNA Binding Protein. The antigen corresponds to amino acid range 1-172 of the target protein.
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Pig
• Product Type: Antibody
• Isotype: IgG