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Cilomilast, MedChemExpress

Product Code. 16470507
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Product Code. 16470507

Brand: Medchem Express HY10790

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Description

MedChemExpress Cilomilast (SB-207499) is a potent, selective and orally active inhibitor of Phosphodiesterase 4 (PDE4), with IC50s of ∼100 and 120 nM for LPDE4 and HPDE4, respectively.

Cilomilast shows selectivity for PDE4 over PDE1, PDE2, PDE3 and PDE5 (IC50=74, 65, >100, and 83 μM, respectively). Cilomilast has anti-inflammatory and immunomodulatory effects and can be used for thr research of asthma and chronic obstructive pulmonary disease (COPD).

Specifications

Chemical Name or Material Cilomilast
CAS 153259-65-5
Color White
Purity Grade Notes Research
Molecular Formula C20H25NO4
Quantity 50 mg
Synonym SB-207499
Solubility Information DMSO : ≥ 100 mg/mL (291.19 mM)
SMILES O=C([C@H]1CC[C@@](C#N)(CC1)C2=CC=C(OC)C(OC3CCCC3)=C2)O
Molecular Weight (g/mol) 343.42
Formula Weight 343.42
Percent Purity 99.89%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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