Invitrogen™ CIDEC Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA530793

Product Code. 13475297

Description

Recommended positive controls: HeLa, HepG2. Predicted reactivity: Pig (81%), Sheep (84%), Bovine (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

DNA fragmentation is one of the critical steps in apoptosis, which is induced by DNA fragmentation factor (DFF). DFF is composed of two subunits, a 40 kDa caspase-activated nuclease (DFF40) and a 45 kDa inhibitor (DFF45). Recently a novel family of cell-death-inducing DFF45-like effectors (CIDEs) has been identified. Human CIDE-3 is a novel member of CIDEs. There are 2 transcripts, CIDE-3 and CIDE-3alpha, were present in HepG2 and A375 cells. Consistent with its chromosome localization at 3p25, a region associated with high frequency loss of heterozygosity in many tumours, CIDE-3 may play an important role in prevention of tumorigenesis.

Specifications

• Antigen: CIDEC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CIDEC
• Gene Alias: cell death activator CIDE-3; cell death inducing DFFA like effector c; cell death-inducing DFFA-like effector c; cell death-inducing DFFA-like effector protein C; CID; cide 3; CIDE3; CIDE-3; CIDE-3alpha; Cidec; fat specific gene 27; fat specific protein 27; fat-specific protein FSP27; Fat-specific protein FSP27 homolog; FPLD5; FSP27
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 63924
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q96AQ7
• Gene Symbols: CIDEC
• Immunogen: Recombinant protein encompassing a sequence within the center region of human CIDEC. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG