Invitrogen™ CIB4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA575610

Product Code. 15962135

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

CIB4 (calcium and integrin-binding family member 4) is a 185 amino acid protein that contains three EF-hand domains. CIB4 is closely related to CIB (CIB has one less EF-hand domain), which is known to bind to Integrin alpha II beta in platelets and is involved in signal transduction. The gene encoding CIB4 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorders itosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstrom syndrome, is caused by mutationsin the ALMS1 gene, which maps to chromosome 2.

Specifications

• Antigen: CIB4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cib4
• Gene Alias: 1700041E20Rik; calcium and integrin binding family member 4; calcium and integrin-binding family member 4; Cib4; KIP4
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 130106, 688819, 73259
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: A0PJX0, Q9D9N5
• Gene Symbols: Cib4
• Immunogen: Synthetic peptide corresponding to residues in Human CIB4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG