Invitrogen™ cIAP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA551700

Product Code. 15799650

Description

Immunogen sequence: QHAKWFPRCE YLIRIKGQEF IRQVQASYPH LLEQLLSTSD SPGDENAESS IIHFEPGEDH SEDAIMMNTP VINAAVEMGF SRSLVKQTVQ RKILATGENY RLVNDLVLDL LNAEDEIREE ERERATEE Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 74%.

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified.

Specifications

• Antigen: cIAP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BIRC3
• Gene Alias: AIP 2; AIP1; Api1; Api2; apoptosis inhibitor 1; apoptosis inhibitor 2; AW107670; baculoviral IAP repeat containing 3; baculoviral IAP repeat-containing 2; baculoviral IAP repeat-containing 3; baculoviral IAP repeat-containing protein 3; Birc2; Birc3; Cellular inhibitor of apoptosis 2; cIAP1; cIAP-1; cIAP2; C-IAP2; cIAP-2; H HIAP1; H MALT2; HAIP1; HIAP1; hIAP-1; HIAP2; IAP homolog; IAP homolog C; IAP1; IAP-1; IAP2; Inhibitor of apoptosis protein 1; MALT2; mammalian IAP homolog C; MIAP1; mIAP-1; MIAP2; MIHB; MIHC; RING finger protein 49; RING-type E3 ubiquitin transferase BIRC3; RNF49; TNFR2-TRAF signaling complex protein; TNFR2-TRAF-signaling complex protein 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 330
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.20 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q13489
• Gene Symbols: BIRC3
• Immunogen: Recombinant protein corresponding to Human cIAP2. Recombinant protein control fragment (Product #RP-101848).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG