Invitrogen™ CHST14 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA567187

Product Code. 15989854

Description

Immunogen sequence: GILAEMKPLPL HPPGREGTAW RGKAPKPGGL SLRAGDADLQ VRQDVRNRTL RAVCGQPGMP RDPWDLPV Highest antigen sequence identity to the following orthologs - mouse 81%, rat 78%.

Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. GlcUA to IdoUA. Appears to have an important role in the formation of the cerbellar neural network during postnatal brain development.

Specifications

• Antigen: CHST14
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHST14
• Gene Alias: 2600016L03Rik; ATCS; carbohydrate (dermatan 4) sulfotransferase 14; carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14; carbohydrate sulfotransferase 14; CHST14; D4ST1; D4ST-1; dermatan 4 sulfotransferase 1; dermatan 4-sulfotransferase 1; dermatan-4-sulfotransferase-1; EDSMC1; hD4ST1; HNK1ST; UNQ1925/PRO4400
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 113189
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8NCH0
• Gene Symbols: CHST14
• Immunogen: Recombinant Human CHST14. Recombinant protein control fragment (Product #RP-105539).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG