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Invitrogen™ CHRNA4 Recombinant Rabbit Monoclonal Antibody (K01_2N54)
Description
CHRNA4 Recombinant Monoclonal Antibody for Western Blot
This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described.
Specifications
Specifications
| Antigen | CHRNA4 |
| Applications | Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | K01_2N54 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 50mM tris glycine with 150mM NaCl, 40% glycerol, 0.05% BSA and 0.01% sodium azide; pH 7.4 |
| Gene | CHRNA4 |
| Gene Accession No. | O70174, P09483, P43681 |
| Gene Alias | a4 nicotinic receptor; acetylcholine receptor; acetylcholine receptor alpha 4 neural; acetylcholine receptor, neuronal, nicotinic, alpha-4 subunit; Acra4; Acra-4; alpha4 nAChR; alpha4-nAChR; BFNC; cholinergic receptor; cholinergic receptor nicotinic alpha 4 subunit; cholinergic receptor, nicotinic alpha 4; cholinergic receptor, nicotinic, alpha 4 (neuronal); cholinergic receptor, nicotinic, alpha 4 subunit; cholinergic receptor, nicotinic, alpha polypeptide 4; CHRNA 4; Chrna4; EBN; EBN1; ENFL1; NACHR; nAChR alpha 4; NACHRA4; NACRA4; NARAC; neuronal acetylcholine receptor subunit alpha-4; Neuronal nicotinic acetylcholine receptor alpha 4 subunit; neuronal nicotinic acetylcholine receptor alpha-4 subunit |
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