CHRNA4 293T Cell Overexpression Lysate (Denatured), Abnova

Product Code. 16103211

Brand: Abnova H00001137T01.100uL

Description

Integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor

This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described.

• Transfected Cell Line: 293T
• Plasmid: pCMV-CHRNA4 full-length
• Host: Human
• Storage Buffer: 1X Sample Buffer (50mM Tris-HCl, 2% SDS, 10% glycerol, 300mM 2-mercaptoethanol, 0.01% Bromophenol blue)

Western Blotting

Specifications

• Cell Line: 293T
• For Use With (Application): Western Blot
• Description: CHRNA4 293T Cell Transient Overexpression Lysate(Denatured)
• Gene Accession No.: BC096292.1
• Molecular Weight (g/mol): 49.72
• pH Range: 6.8
• Plasmid: pCMV-CHRNA4 full-length
• Quality Control Testing: Transient overexpression cell Lysate was tested with Anti-CHRNA4 antibody (H00001137-B01) by western blotting
• Quantity: 100 μL
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Host Species: Human
• Content And Storage: Store at -80°C. Aliquot to avoid repeated freezing and thawing.