Invitrogen™ CHP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA529876

Product Code. 13464217

Description

Recommended positive controls: HeLa, HepG2, mouse liver, rat liver. Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (90%), Xenopus laevis (94%), Chicken (96%), Rhesus Monkey (100%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis.

Specifications

• Antigen: CHP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHP1
• Gene Alias: 1500003O03Rik; AA960066; AI046351; Cahp; calcineurin B homolog; calcineurin B homologous protein 1; Calcineurin B-like protein; calcineurin homologous protein; calcineurin like EF-hand protein 1; calcineurin-like EF hand protein 1; calcineurin-like EF-hand protein 1; calcium binding protein P22; calcium-binding protein CHP; Calcium-binding protein p22; CHP; chp1; Chromo domain-containing protein 1; chromodomain protein Chp1; EF-hand Ca2+-binding protein p22; EF-hand calcium-binding domain-containing protein p22; p22; p24; si:dkey-41n20.1; sid 470; Sid470; Sid470p; SLC9A1 binding protein; SLC9A1BP; SPAC18G6.02c; Unknown (protein for MGC:127971); Unknown (protein for MGC:63904); vac; Wrch2; wu:fc69b04; zgc:63904
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11261, 56398, 64152
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P61022, P61023, Q99653
• Gene Symbols: CHP1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Calcium binding protein p22. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG