Cholesterol, 95%, Thermo Scientific Chemicals

Description

A laboratory purified preparation of the animal sterol, Cholesterol, CAS # 57-88-5, is available in powder form for experimental use.

Cholesterol is used in the preparation of liposome. It is used to control the functions of transporters and coordinating cell proteins present in plasma membrane. It acts as a part of cell membranes. It benefits in rapid diagnostics. It is a component of all biological membranes and inhibits basal channel activity in the brain.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• Cholesterol (cholesterin, cholesteryl alcohol) is a lipid sterol found in vertebrate cell membranes
• Cholesterol is a cholestanoid, a class of molecule that contains the C-27 cholestane motif
• A precursor of many steroids and sex hormones in animals including cortisol, aldosterone, testosterone, progesterone, and estrogen
• It plays a role in neurotransmission and is crucial for organ systems, such as immune, reproductive and endocrine systems

Applications

• Suitable for in vitro and in vivo applications
• Stabilized in powder form for laboratory use only

Specifications

Chemical Identifiers

• CAS: 57-88-5
• Molecular Formula: C27H46O
• Molecular Weight (g/mol): 386.664
• MDL Number: MFCD00003646
• InChI Key: HVYWMOMLDIMFJA-DPAQBDIFSA-N
• Synonym: cholesterol, cholesterin, cholest-5-en-3beta-ol, cholesteryl alcohol, cholestrin, cordulan, dusoline, dusoran, provitamin d, cholesterine
• PubChem CID: 5997
• ChEBI: CHEBI:16113
• IUPAC Name: (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
• SMILES: CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C

• Melting Point: 147°C to 150°C
• Density: 1.067
• Boiling Point: 360°C
• Assay Percent Range: 95%
• Quantity: 250 g
• Beilstein: 1915888
• Merck Index: 14,2201
• Solubility Information: Soluble in alcohols,ether,chloroform,petroleum ether,pyridine,isopropyl myristate,acetone,ethylacetate,benzene,fats,oils and dioxane.
• Optical Rotation: −36° (c=2 in dioxane)
• Formula Weight: 386.66
• Percent Purity: 95%
• Chemical Name or Material: Cholesterol

RUO – Research Use Only