Invitrogen™ CHN2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5119022

Product Code. 17750434

Description

CHN2 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specifications

• Antigen: CHN2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Chn2
• Gene Alias: 1700026N20Rik; 4930557O16Rik; ARHGAP3; BCH; beta chimaerin; beta chimerin; beta3-chimaerin; beta-chimaerin; Beta-chimerin; chimerin (chimaerin) 2; chimerin 2; chimerin, beta-2; chimerin, testis-specific; Chn2; CHN2-3; OTTHUMP00000202260; Rho GTPase-activating protein 3; RHOGAP3; rho-GTPase-activating protein 3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 84031
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: Q03070
• Gene Symbols: Chn2
• Immunogen: Recombinant protein Chimerin 2. The antigen corresponds to amino acid range 101-280 of the target protein.
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG