Invitrogen™ CHN2 Monoclonal Antibody (E.584.10)

Rat Monoclonal Antibody

Brand:  Invitrogen™ MA514967

Product Code. 11584931

Description

It is not recommended to aliquot this antibody.

This gene is a member of the chimerin family and encodes a protein with a phorbol-ester/DAG-type zinc finger, a Rho-GAP domain and an SH2 domain. This protein has GTPase-activating protein activity that is regulated by phospholipid binding and binding of diacylglycerol (DAG) induces translocation of the protein from the cytosol to the Golgi apparatus membrane. The protein plays a role in the proliferation and migration of smooth muscle cells. Decreased expression of this gene is associated with high-grade gliomas and breast tumors, and increased expression of this gene is associated with lymphomas. Mutations in this gene have been associated with schizophrenia in men. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specifications

• Antigen: CHN2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: Chn2
• Gene Alias: 1700026N20Rik; 4930557O16Rik; ARHGAP3; BCH; beta chimaerin; beta chimerin; beta3-chimaerin; beta-chimaerin; Beta-chimerin; chimerin (chimaerin) 2; chimerin 2; chimerin, beta-2; chimerin, testis-specific; Chn2; CHN2-3; OTTHUMP00000202260; Rho GTPase-activating protein 3; RHOGAP3; rho-GTPase-activating protein 3
• Host Species: Rat
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1124, 69993, 84031
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Clone: E.584.10
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5
• Gene Accession No.: P52757, Q03070, Q80XD1
• Gene Symbols: Chn2
• Immunogen: Full-length recombinant human β2-Chimerin.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2a