Invitrogen™ CHMP2A Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA587855

Product Code. 16536231

Description

Immunogen sequence: MDLLFGRRKT PEELLRQNQR ALNRAMRELD RERQKLETQE KKIIADIKKM AKQGQMDAVR IMAKDLVRTR RYVRKFVLMR ANIQAVSLKI QTLKSNNSMA QAMKGVTKAM GTMNRQLKLP QIQKIMMEFE RQAEIMDMKE EMMNDAIDDA MGDEEDEEES DAVVSQVLDE LGLSLTDELS NLPSTGGSLS VAAGGKKAEA AASALADADA DLEERLKNLR RD; Positive Samples: A-431, HepG2, SW480; Cellular Location: Cytoplasmic side, Late endosome membrane, Peripheral membrane protein.

CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A is required for both MVB formation and regulation of cell cycle progression.

Specifications

• Antigen: CHMP2A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHMP2A
• Gene Alias: 1500016L11Rik; BC2; BC-2; Charged multivesicular body protein 2a; CHMP2; CHMP2A; chromatin modifying protein 2A; chromatin-modifying protein 2a; fj10d05; hypothetical protein LOC523847; mVps2; putative breast adenocarcinoma marker; putative breast adenocarcinoma marker (32kD); putative breast adenocarcinoma marker BC-2; RGD1305050; Vacuolar protein sorting-associated protein 2; vacuolar protein sorting-associated protein 2-1; vacuolar protein-sorting-associated protein 2; VPS2; VPS2 homolog A; vps2-1; VPS2A; wu:fi18h03; wu:fj10d05; zgc:55361
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27243
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.26 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O43633
• Gene Symbols: CHMP2A
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human CHMP2A (NP_0552681).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG