Invitrogen™ CHM Recombinant Rabbit Monoclonal Antibody (JE61-83)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA544856

Product Code. 17850156

Description

CHM Recombinant Monoclonal Antibody for Western Blot, IHC (P), ICC/IF, Flow

Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation.

Specifications

• Antigen: CHM
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 40% glycerol, 0.05% BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P24386, P37727, Q9QXG2
• Gene Symbols: CHM
• Immunogen: Synthetic peptide within human CHM aa 36-85/653.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: JE61-83
• Conjugate: Unconjugated
• Gene: CHM
• Gene Alias: CHM; CHM, Rab escort protein 1; choroideraemia protein homolog; choroideremia (Rab escort protein 1); Choroideremia protein; Choroideremia protein homolog; choroidermia; choroidermia (RAB escort protein 1); DXS540; GGTA; HSD-32; Rab escort protein 1; rab proteins geranylgeranyltransferase component A 1; REP1; REP-1; TCD; TCD protein
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1121, 12662, 24942
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid