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Chloromethyl pivalate, 97%, Thermo Scientific Chemicals
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Description
Chloromethyl pivalate acts as an intermediate in the synthesis of active pharmaceutical ingredients. It is also involved in the acylation reaction with 9-(2-phosphonylmethoxyethyl)adenine. It serves as a protecting reagent used for the N-protection of amines. It is also employed in the preparation of pivaloyloxy methyl ester of ofloxacin as a prodrug. Further, it is used to prepare sulbactam pivoxil by reaction with sodium salt of sulbactam. In addition to this, it is used as a reagent during the synthesis of an isoindoline-annulated and continuous-flow organic synthesis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Chloromethyl pivalate acts as an intermediate in the synthesis of active pharmaceutical ingredients. It is also involved in the acylation reaction with 9-(2-phosphonylmethoxyethyl)adenine. It serves as a protecting reagent used for the N-protection of amines. It is also employed in the preparation of pivaloyloxy methyl ester of ofloxacin as a prodrug. Further, it is used to prepare sulbactam pivoxil by reaction with sodium salt of sulbactam. In addition to this, it is used as a reagent during the synthesis of an isoindoline-annulated and continuous-flow organic synthesis.
Solubility
Miscible with most organic solvents. Immiscible with water.
Notes
Incompatible with strong oxidizing agents.
Specifications
Density | 1.045 |
Boiling Point | 146°C to 148°C |
Flash Point | 40°C (104°F) |
Linear Formula | (CH3)3CCO2CH2Cl |
Refractive Index | 1.417 |
Quantity | 25 g |
UN Number | UN2924 |
Beilstein | 1560838 |
Solubility Information | Miscible with most organic solvents. Immiscible with water. |
Formula Weight | 150.6 |
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RUO – Research Use Only