Invitrogen™ CHKB Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA553847

Product Code. 15761781

Description

Immunogen sequence: CEWVYDYTHE EWPFYKARPT DYPTQEQQLH FIRHYLAEAK KGETLSQEEQ RKLEEDLLVE VSRYALASHF FWGLWS Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 84%.

The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. Choline kinase, the initial enzyme in the sequence, plays a role in cell growth proliferation. A related protein, ChoKB (also, known as choline kinase beta), is a 395 amino acid enzyme that catalyzes the phosphorylation of choline by ATP in the presence of magnesium, thereby yielding phosphocholine and ADP. Like all choline kinases, ChoKB possesses ethanoalamine kinase activity and catalyzes the phosphorylation of ethanolamine. The gene encoding ChoKB is located less than 1 kb upstream of the CPT1B gene, suggesting that the ChoKB gene may regulate transcription CPT1B. In mice, mutations and/or deletions in the gene encoding ChoKB are the cause of hindlimb muscular dystrophy and neonatal bone deformity.

Specifications

• Antigen: CHKB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHKB
• Gene Alias: Chetk; CHKB; Chkl; choline kinase beta; Choline kinase-like protein; choline/ethanolamine kinase; choline/ethanolamine kinase beta; choline/ethanolamine kinase-b; choline/ethanolaminekinase; CK; Ck/Ek; Ck/Ek-beta; CKB; CKEKB; EK; EKB; ethanolamine kinase; Ethanolamine kinase beta; MDCMC
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1120
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9Y259
• Gene Symbols: CHKB
• Immunogen: Recombinant protein corresponding to Human CHKB. Recombinant protein control fragment (Product #RP-92367).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG