Invitrogen™ CHCHD3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA531578

Product Code. 13496097

Description

Recommended positive controls: 293T, A431, Jurkat, Raji, mouse liver. Predicted reactivity: Mouse (89%), Rat (83%), Pig (91%), Sheep (89%), Rhesus Monkey (95%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology.

Specifications

• Antigen: CHCHD3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CHCHD3
• Gene Alias: 0610041L09Rik; 1700039J09Rik; AW558177; CHCHD3; coiled-coil-helix-coiled-coil-helix domain containing 3; Coiled-coil-helix-coiled-coil-helix domain-containing protein 3; coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial; FLJ20420; Mic19; MICOS complex subunit MIC19; MINOS3; mitochondrial inner membrane organizing system 3; PPP1R22; protein phosphatase 1, regulatory subunit 22
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54927, 66075
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9CRB9, Q9NX63
• Gene Symbols: CHCHD3
• Immunogen: Recombinant protein encompassing a sequence within the center region of human CHCHD3. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG