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Ch 55, Tocris Bioscience™
Potent RAR agonist
£166.00 - £633.01
Chemical Identifiers
CAS | 110368-33-7 |
---|---|
Molecular Formula | C24H28O3 |
Molecular Weight (g/mol) | 364.485 |
InChI Key | FOUVTBKPJRMLPE-FMIVXFBMSA-N |
Synonym | 3,5-di-tert-butylchalcone, 4-1e-3-3,5-di-tert-butylphenyl-3-oxoprop-1-en-1-yl benzoic acid, 4-3-3,5-di-t-butylphenyl-3-oxo-1-propenyl benzoic acid, e-4-3-3,5-bis 1,1-dimethylethyl phenyl-3-oxo-1-propenyl benzoic acid, benzoic acid, 4-3-3,5-bis 1,1-dimethylethyl phenyl-3-oxo-1-propenyl-, e, 3,5-di-tert-butylchalcone-4'-carboxylic acid, e-4-3,5-di-t-butylphenyl-3-oxopropenyl benzoic acid, 4-3-3,5-di-tert-butylphenyl-3-oxo-1-propenyl benzoic acid, 4-e-3-3,5-ditert-butylphenyl-3-oxo-prop-1-enyl benzoic acid, 4-e-3-3,5-ditert-butylphenyl-3-oxoprop-1-enyl benzoic acid |
PubChem CID | 6184667 |
IUPAC Name | 4-[(E)-3-(3,5-ditert-butylphenyl)-3-oxoprop-1-enyl]benzoic acid |
SMILES | CC(C)(C)C1=CC(=CC(=C1)C(=O)C=CC2=CC=C(C=C2)C(=O)O)C(C)(C)C |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
18055162
|
Tocris Bioscience
2020/10 |
10 mg |
£166.00
10mg |
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18025062
|
Tocris Bioscience
2020/50 |
50 mg |
£633.01
50mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Highly potent synthetic retinoid that has high affinity for RAR-α and RAR-β receptors and low affinity for cellular retinoic acid binding protein (CRABP). Inhibits rabbit tracheal epithelial cell differentiation by inhibiting transglutaminase and increasing cholesterol sulfate (EC50 values are 0.02 and 0.03 nM respectively). Induces differentiation of embryonic carcinoma F9 and melanoma S91 cells (EC50 values are 0.26 and 0.5 nM respectively) and inhibits the induction of ornithine decarboxylase activity in 3T6 fibroblasts (EC50 = 1 nM).Chemical Identifiers
110368-33-7 | |
364.485 | |
3,5-di-tert-butylchalcone, 4-1e-3-3,5-di-tert-butylphenyl-3-oxoprop-1-en-1-yl benzoic acid, 4-3-3,5-di-t-butylphenyl-3-oxo-1-propenyl benzoic acid, e-4-3-3,5-bis 1,1-dimethylethyl phenyl-3-oxo-1-propenyl benzoic acid, benzoic acid, 4-3-3,5-bis 1,1-dimethylethyl phenyl-3-oxo-1-propenyl-, e, 3,5-di-tert-butylchalcone-4'-carboxylic acid, e-4-3,5-di-t-butylphenyl-3-oxopropenyl benzoic acid, 4-3-3,5-di-tert-butylphenyl-3-oxo-1-propenyl benzoic acid, 4-e-3-3,5-ditert-butylphenyl-3-oxo-prop-1-enyl benzoic acid, 4-e-3-3,5-ditert-butylphenyl-3-oxoprop-1-enyl benzoic acid | |
4-[(E)-3-(3,5-ditert-butylphenyl)-3-oxoprop-1-enyl]benzoic acid |
C24H28O3 | |
FOUVTBKPJRMLPE-FMIVXFBMSA-N | |
6184667 | |
CC(C)(C)C1=CC(=CC(=C1)C(=O)C=CC2=CC=C(C=C2)C(=O)O)C(C)(C)C |
Specifications
110368-33-7 | |
3,5-di-tert-butylchalcone, 4-1e-3-3,5-di-tert-butylphenyl-3-oxoprop-1-en-1-yl benzoic acid, 4-3-3,5-di-t-butylphenyl-3-oxo-1-propenyl benzoic acid, e-4-3-3,5-bis 1,1-dimethylethyl phenyl-3-oxo-1-propenyl benzoic acid, benzoic acid, 4-3-3,5-bis 1,1-dimethylethyl phenyl-3-oxo-1-propenyl-, e, 3,5-di-tert-butylchalcone-4'-carboxylic acid, e-4-3,5-di-t-butylphenyl-3-oxopropenyl benzoic acid, 4-3-3,5-di-tert-butylphenyl-3-oxo-1-propenyl benzoic acid, 4-e-3-3,5-ditert-butylphenyl-3-oxo-prop-1-enyl benzoic acid, 4-e-3-3,5-ditert-butylphenyl-3-oxoprop-1-enyl benzoic acid | |
CC(C)(C)C1=CC(=CC(=C1)C(=O)C=CC2=CC=C(C=C2)C(=O)O)C(C)(C)C | |
364.485 | |
364.47 | |
Ch 55 |
C24H28O3 | |
FOUVTBKPJRMLPE-FMIVXFBMSA-N | |
4-[(E)-3-(3,5-ditert-butylphenyl)-3-oxoprop-1-enyl]benzoic acid | |
6184667 | |
>98% |
Safety and Handling
Recommended Storage : Store at Room Temperature