CGRP Monoclonal Antibody (4901), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA547687

Product Code. 17836938

Description

Specific for Calcitonin Gene Related Peptide. Also recognizes rat beta-CGRP and human alpha-CGRP (10-fold less sensitivity compared to rat alpha-CGRP). Suggested positive controls are dorsal root ganglia, pancreas and gut.

This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: CGRP
• Classification: Monoclonal
• Concentration: Lot-Specific
• Formulation: 10mM HEPES with 100μg/mL BSA, 150mM NaCl, 50% glycerol and no preservative; pH 7.5
• Gene Accession No.: P01256, P01257
• Gene Symbols: Calca
• Immunogen: Purified rat alpha-CGRP.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Rat
• Form: Liquid

• Applications: Immunocytochemistry
• Clone: 4901
• Conjugate: Unconjugated
• Gene: Calca
• Gene Alias: alpha-type CGRP; CA; Cal1; CAL6; CALC; Calc1; Calca; calcitonin; calcitonin 1; Calcitonin carboxyl-terminal peptide; Calcitonin gene-related peptide 1; calcitonin gene-related peptide I; calcitonin related polypeptide alpha; calcitonin/calcitonin-related polypeptide, alpha; calcitonin; calcitonin gene-related peptide 1; calcitonin-related polypeptide alpha; CCALCI; CCP; Cgrp; CGRP1; CGRP-1; CGRP-I; Ct; Ctn; Katacalcin; KC; MGC126648; PCT; PDN-21; prepro-alpha-calcitonin gene-related peptide; RAT calcitonin; RATCAL6
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 24241
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Isotype: IgG2a