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Tocris Bioscience™ CGP 57380

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Quantity:
1 mg
10 mg
50 mg
Unit Size:
10mg
1mg
50mg
Description
Inhibitor of MAP-kinase interacting kinase-1 (Mnk1, MKNK1) (IC50 = 2.2 μM) that displays selectivity over p38, JNK1, ERK1, ERK2, PKC and c-src family kinases. Blocks phosphorylation of eIF4E in cellular assays (IC50 = 3 μM) and inhibits LPS-induced TNFα expression in macrophages.
Specifications
Specifications
| Quantity | 1 mg |
| Formula Weight | 244.23 |
| Purity | >98% |
| Molecular Weight (g/mol) | 244.233 |
| Chemical Name or Material | CGP 57380 |
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