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Tocris Bioscience™ CFTRinh 172
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Product Code. 30001049
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 30001049

Brand: Tocris Bioscience™ 3430/10

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This item is not returnable. View return policy

Description

Voltage-independent, selective CFTR chloride channel blocker

Voltage-independent, selective CFTR chloride channel blocker (Ki = 300 nM) that alters channel gating. Blocks intestinal fluid secretion induced by cholera toxin and Escherichia coli and suppresses cyst growth in animal models of polycystic kidney disease. Orally active. Inhibits mitochondrial respiration and increases reactive oxygen species (ROS) production independently of CFTR in several cell lines.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 307510-92-5
Molecular Formula C18H10F3NO3S2

Specifications

Quantity 10 mg
Formula Weight 409.4
Purity >98%
Molecular Weight (g/mol) 409.397
Chemical Name or Material CFTRinh 172
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